Penélope Cruz and Johnny Depp have fun at 'Murder on the Orient Express' premiere

It was a reunion for Penélope Cruz and pal Johnny Depp at the London premiere of their latest film, Murder on the Orient Express. The Spanish actress, 43, and the 54-year-old shared a special moment on the November 2 carpet when the Johnny jokingly pointed at Javier Bardem’s wife and said, “I know you.” The Murder on the Orient Express is the first time that Johnny and Penélope have shared the silver screen since starring together in 2011’s Pirates of the Caribbean: On Strange Tides

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murder-orient-express-londonVIEW GALLERY Johnny Depp and Leslie Odom Jr. (second from the right), joined Penélope at the premiere of Murder on the Orient Express Photo: Dave J Hogan/Getty Images

The Hollywood stars shared the screen for the first time in the 2001 cult classic Blow. Noticeably absent from the affair, was the Oscar-winning actress' husband and Johnny's friend, Javier Bardem. Nonetheless, the mom-of-two worked the carpet posing by herself and with her co-stars.

MORE: Penélope on how motherhood changed her and working with Javier

Penélope stunned for the occasion wearing a black dress by one of Kate Middleton's go-to designers, Temperley London. Javier's leading lady stole the show in the gown that featured quartered sleeves and a thigh-high split, as well as sequins that shined under the lights of London's Royal Albert Hall.

penelope-cruz-temperley-londonVIEW GALLERY The Oscar-winning actress stunned in a dress by Temperley London Photo: Karwai Tang/WireImage

MORE: Penélope and Javier begin filming in Spain 

Penélope completed her glamorous look with black peep-toe heels and Atelier Swarovski jewelry. The brunette beauty wore her long dark tresses down in loose waves. Penélope and Johnny were also joined on the carpet by their co-stars Leslie Odom Jr., Olivia Colman, Michelle Pfeiffer and Dame Judy Dench. The all-star film, based on the novel by Agatha Christie, opens in theaters November 10

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